Chayada Chanasriyotin,
Department of Otolaryngology, Faculty of Medicine, Vajira Hospital, Navamindradhiraj University, Bangkok, Thailand.
Title: Incidence and Associating Factors of Post-Thyroid-Lobectomy Hypothyroidism in Thai Patients at Vajira Hospital: A Retroprospective Review.
Biography
Biography: Chayada Chanasriyotin,
Abstract
Background: A retrospective review of 80 patients who had undergone hemithyroidectomy from 2017 to 2022 at Vajira Hospital. Patients were analyzed for age, sex, weight, height, BMI, underlying medical problems, pre- and postoperative levels of thyroid stimulating hormone (TSH), histologic diagnosis, weight of resected tissue, histologic evidence of thyroiditis, and lag time to diagnosis of hypothyroidism. Kaplan-Meier survival and log rank test was performed.
Results: Of these 80 patients, 38 (47.5%) became hypothyroid post surgery. Using Kaplan-Meier survival analysis, we found probabilities of hypothyroidism at 3, 6, 12 months to be 40%, 44.4% and 49.8%, respectively. Eighteen hypothyroid patients (22.5%) needed supplemental thyroxine within 3 months post surgery while 2 patients (2.5%) required the supplement at 6 months and 2 more patients (2.5%) did so at 12 months. Sixteen patients (20%) developed hypothyroidism but did not require supplemental thyroxine. The remaining 42 patients (52.5%) were euthyroid. No significant difference was seen between the two groups with respect to age, sex, weight, BMI, comorbidities, TSH levels, histology, lag time of diagnosis, or weight of resected gland (p>0.05).
Conclusions: We conclude that hypothyroidism after hemithyroidectomy is a common occurrence. It is recommended to follow patients closely for at least 1 year post surgery. Monitoring should include scheduled serial serum TSH draws.