Wetchayan Chansarn
Department of Orthopaedics, Faculty of Medicine, Vajira hospital, Navamindradhiraj University, Thailand
Title: Associating Factors of Osteoporosis in post-menopausal women at Vajira Hospital, Thailand
Biography
Biography: Wetchayan Chansarn
Abstract
Background and objective: Prevalence of postmenopausal osteoporosis is increasing. Osteoporosis increases the chance of fractures which increased morbidity and mortality rates. This study aims to study 3 risk factors for osteoporosis; age, body mass index, age at menopause. Methods: This cross-sectional study in postmenopausal women was evaluated for bone mineral density using Dual energy X-ray absorptiometry at nuclear medicine department in Vajira Hospital from January 2021 to December 2021. A total of 1,201 women were enrolled, 494 with osteoporosis and 707 without osteoporosis. We use criteria for the diagnosis of osteoporosis according to WHO criteria. The baseline data and risk factors; age, body mass index (BMI), and menopause age, were collected from DXA. Results: From total 1,201 populations, the mean age was 69.81 + 9.11, mean menopausal age was 48.34 + 5.69 and mean BMI was 24.98 + 4.78. In the Adjust Odds ratio analysis, the age groups 60-69, 70-79 and 80 more at risk of developing osteoporosis than 1.830, 2.687 and 6.028 times, respectively, compared to the reference age group of 50-59 years old. The underweight group and normal group have higher risk of developing osteoporosis were 5.467, 2.002 times, respectively, compared to the reference overweight group. The later menopause age in every 1 year, the lower risk of osteoporosis by 2.3 percent. Conclusion: Advance age, low BMI and menopausal age are statistically significant associated factors with the occurrence of osteoporosis in postmenopausal women.